Short Advanced Preclinical Models

Advanced preclinical models contribute to various areas of biomedical research and personalized medicine, offering new insights into disease mechanisms and potential therapeutic interventions. Examples of advanced preclinical models: Induced Pluripotent Stem (iPS) Cells: Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo. Cardiac Organoids: Scientists engineer […]

Ovarian Cancer

Types of Ovarian Cancer: Overview of OVERIAN CANCER Types Understanding Different Forms of Overian Cancer Epithelial Ovarian Cancer (EOC): This is the most common type of ovarian cancer, accounting for about 90% of cases. It arises from the cells that cover the outer surface of the ovary. Germ Cell Tumors: These rare ovarian cancers develop […]

Head and Neck Cancers

Head and neck cancers can involve both germline and somatic genetic alterations that contribute to their development and progression. Germline mutations are inherited genetic changes present in all cells of an individual’s body, while somatic mutations are acquired alterations that occur specifically in the cancerous cells of the head and neck tissues.  Germline Genes: Somatic […]

Breast Cancer

Population-based breast cancer screening programs, such as mammography screening, aim to detect breast cancer at an early stage when treatment is more effective. These screening programs vary by country and are often targeted at women within certain age groups, such as women aged 50 to 74 years in many Western countries. Regular screening can lead […]

Medullary Thyroid Cancer

Medullary thyroid cancer (MTC) can involve both germline and somatic genetic alterations that contribute to its development and progression. Germline mutations are inherited genetic changes present in all cells of an individual’s body, while somatic mutations are acquired alterations that occur specifically in the cancerous cells of the thyroid gland.  Genetic Basis of Medullary Thyroid […]

Chronic Lymphocytic Leukemia

Germline Genes: ATM (Ataxia Telangiectasia Mutated) Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo. NOTCH1 Germline polymorphisms in the NOTCH1 gene have been implicated in CLL susceptibility. NOTCH1 is involved in cell signaling pathways that regulate cell proliferation and differentiation. TERT (Telomerase Reverse Transcriptase) Accordion […]

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) can be classified into different types or subtypes based on various factors, including the presence of specific genetic or molecular abnormalities, the lineage of the leukemia cells, and the patient’s clinical characteristics. Staging in AML refers 
to the extent of the disease and helps guide treatment decisions.  Subtypes of AML Cytogenetic […]