Myocardial Insufficiency
Overall, myocardial insufficiency is a complex and chronic condition that requires comprehensive management and ongoing medical care. Multidisciplinary approaches involving cardiologists, primary care physicians, nurses, and other healthcare professionals are essential for optimizing patient outcomes and quality of life. Key genes and genetic factors associated with myocardial insufficiency include:
Thoracic Aortic Aneurysm
Several genes have been implicated in the development of thoracic aortic aneurysms (TAAs). Mutations in these genes can predispose individuals to TAAs, often as part of hereditary connective tissue disorders or familial forms of TAAs. Here are some of the key genes associated with TAAs:
Long QT syndrome
Mutations in at least 15 genes have been linked to LQTS. These genes encode ion channels or channel-associated proteins involved in cardiac repolarization. The most common genes associated with LQTS include:
Aortic stenosis
Aortic stenosis (AS) is primarily a degenerative condition associated with aging and calcification of the aortic valve. However, there are also genetic factors that can predispose individuals to develop AS. Here are some of the key genes associated with aortic stenosis:
Brugada Syndrome
Key genes associated with ARVC include:
Marfan Syndrome
Marfan syndrome is primarily caused by mutations in the FBN1 gene, which provides instructions for making fibrillin-1, a protein that is essential for the formation of elastic fibers in connective tissue.
Arrhythmogenic Right Ventricular Cardiomyopathy
Key genes associated with ARVC include:
Andersen-Tawil Syndrome
The remaining genes associated with ATS include:
Coronary Artery Disease (CAD)
Key genes and genetic factors associated with CAD include:
