MOSAIC RESEARCH PLATFORM

Platform utilizing artificial intelligence for integrating and analyzing multiomic and clinical data to obtain new knowledge and tools for widely accessible, personalized preventive, diagnostic, and medical therapeutic practices.

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Planned Effects

The MOSAIC platform will enable the use of AI to understand the pathomechanisms of selected diseases better, identify specific biomarkers for them, and develop new therapeutic strategies. The advanced AI algorithms will support decisions regarding the diagnosis and treatment of patients.

The MOSAIC Platform will apply AI algorithms to:

Deep understanding of disease pathomechanisms
Support clinical decisions
Create new personalized therapies

The MOSAIC Platform will apply AI algorithms to:

Planowane efekty

CategoryTechnologies

Patch Clamp

Patch clamp is vital in neuroscience, measuring cell electrical activity by sealing a micropipette onto a membrane area for precise analysis.

TIRF Microscopy

TIRF microscopy offers high-resolution imaging near the cell membrane, providing insights into dynamic cellular processes in biology and neuroscience.

Spinning Disc Confocal Microscopy

Spinning disc confocal microscopy offers high-resolution live-cell imaging, crucial for studying dynamic cellular processes in biology and neuroscience.

Spatial Transcriptomics

Spatial transcriptomics integrates RNA sequencing with spatial data, mapping gene expression to understand disease progression, particularly in cancer, for targeted interventions.

Micropatterning

Micropatterning technologies, such as innovations like Primo Alveole, represent a sophisticated approach in biomedical research.

Microfluidics

Microfluidics revolutionizes biomedical research by enabling accurate preclinical models like organoids for studying disease mechanisms and drug responses.

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CategoryMultiomics

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Transcriptomics

explores the complete set of RNA transcripts produced by a cell or organism. It unveils the dynamic expression of genes, shedding light on cellular activities and responses. By deciphering the transcriptome, researchers gain a deeper understanding of how genes are regulated and function in various biological processes.

Genomics

Genomics is the study of an organism's complete set of DNA, encompassing all of its genes. It provides insights into the genetic variations that contribute to traits, diseases, and evolution. Genomic studies employ cutting-edge technologies to decode the order of nucleotides in DNA, revealing the blueprint of life.

Epigenomics

Epigenomics investigates the modifications to DNA and its associated proteins that control gene expression without altering the underlying genetic code. This field delves into the intricate regulatory mechanisms, offering insights into how environmental factors and lifestyle influence gene activity. Understanding epigenetic patterns is crucial for unravelling the complexity of diseases and development.

Proteomics

Proteomics examines the entire complement of proteins within a cell or organism. Researchers gain insights into cellular functions, signalling pathways, and disease mechanisms by identifying, quantifying, and characterizing proteins. Proteomic studies play a pivotal role in advancing our understanding of the functional dynamics of biological systems.

RESEARCH AREAS

Cardiology

Cardiac diseases pose a significant global health challenge, impacting millions. Conditions like CAD, heart failure, and arrhythmias are major contributors to morbidity and mortality. Understanding genetic factors, such as mutations in LDLR and MTHFR genes is crucial for targeted interventions to mitigate the disease impact.

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RESEARCH AREAS

Oncology

Oncology is of paramount importance in the realm of healthcare due to the pervasive impact of cancer globally. Cancer, a leading cause of morbidity and mortality, touches the lives of millions, emphasizing the urgency of effective strategies. The intricate nature of cancer necessitates a multidisciplinary approach involving medical, surgical and radiation oncologists.

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The project to create the MOSAIC intelligent platform is carried out by the European Center for Bioinformatics and Genomics consortium consisting of: